Pharmacotherapeutic group: Mineral supplements, calcium ATC code: A12AA07
Mechanism of action:
Calcium is a mineral element necessary for maintaining body fluid balance and ensuring the proper function of many regulatory mechanisms in the body. It acts as an activator of a number of enzymatic systems. It is essential for the formation of bones and teeth and for the function of muscular and nervous tissues. It is of fundamental importance for cardiac and renal function, respiratory function, blood coagulation, and membrane permeability including capillary permeability.
⚠️ Warnings
Calcium chloride solutions cause local gastric irritation and should therefore be administered in as dilute a concentration as possible. A highly diluted solution causes less gastric irritation when administered orally.
In patients with mild hypercalciuria and in mild to moderate renal insufficiency, urinary calcium excretion should be monitored and the dose reduced or the medicine discontinued as necessary.
When co-administered with vitamin D (in doses greater than 1,000 IU), the total daily dose must not exceed 1,000 mg of calcium and urinary calcium excretion should be monitored.
In patients prone to urinary calculi, a higher fluid intake is recommended.
This medicine contains 20 mg of ethanol per teaspoon (5 ml) and 60 mg of ethanol per tablespoon (15 ml), equivalent to 0.5% (v/v). The amount in one teaspoon of this medicine is equivalent to less than 0.5 ml of beer or 0.2 ml of wine; the amount in one tablespoon of this medicine is equivalent to less than 1.5 ml of beer or 0.6 ml of wine. The small amount of alcohol in this medicine has no noticeable effect.
This medicine contains 67.2 g of sucrose per 100 ml of solution (one teaspoon of solution contains 3.36 g of sucrose, one tablespoon of solution contains 10.08 g of sucrose). Patients with rare hereditary problems of fructose intolerance, glucose-galactose malabsorption, or sucrase-isomaltase insufficiency must not take this medicine. This must be taken into account in patients with diabetes mellitus.
This medicine contains 1 mg of sodium benzoate (E 211) per ml of solution. Increased bilirubinaemia following displacement of bilirubin from albumin may increase neonatal jaundice, which may progress to kernicterus (deposits of unconjugated bilirubin in brain tissue).