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Manufacturer
正和製藥股份有限公司新營廠 (TW)
ATC Code
N06AX05
Source
TFDA
USDailyMed:Trazodone
N06AX05(WHO)
AU:S4(Prescription only)BR:Class C1(Other controlled substances)CA:℞-onlyUK:POM(Prescription only)US:℞-onlyIn general: ℞ (Prescription only)
2-{3-[4-(3-Chlorophenyl)piperazin-1-yl]propyl}[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one
19794-93-5Y
5533
213
DB00656Y
5332Y
YBK48BXK30
D08626Yas HCl:D00820Y
CHEBI:9654Y
ChEMBL621Y
DTXSID5045043
Interactive image
Clc4cccc(N3CCN(CCCN1/N=C2/C=C\C=C/N2C1=O)CC3)c4
InChI=1S/C19H22ClN5O/c20-16-5-3-6-17(15-16)23-13-11-22(12-14-23)8-4-10-25-19(26)24-9-2-1-7-18(24)21-25/h1-3,5-7,9,15H,4,8,10-14H2YKey:PHLBKPHSAVXXEF-UHFFFAOYSA-NY
Trazodoneis anantidepressantmedicationused to treatmajor depressive disorder,anxiety disorders, andinsomnia.It is aphenylpiperazinecompound of theserotonin antagonist and reuptake inhibitor(SARI) class.The medication is takenorally.
Common side effects includedry mouth, feeling faint, vomiting, and headache.More serious side effects may includesuicide,mania,irregular heart rate, andpathologically prolonged erections.It is unclear if use duringpregnancyorbreastfeedingis safe.Trazodone also has sedating effects.
Trazodone was approved for medical use in the United States in 1981.It is available as ageneric medication.In 2023, it was the 21st most commonly prescribed medication in the United States and the fifth most common antidepressant, with more than 24million prescriptions.
⚠️ Warnings
• Caution should be exercised in patients with history of depression, mental problems, suicidal thoughts, alcoholism, irregular heartbeat, low blood pressure, cancer, heart attack, any allergy, who are taking other medications, during pregnancy and breastfeeding.
• It may cause drowsiness, dizziness, or blurred vision, do not drive a car or operate machinery and get up slowly from bed while taking this medication.
• Avoid alcohol consumption.
• It should not be used in children.
• Patient may develop with increased risk of suicidal thoughts; watch them carefully.
♦
Patient may develop with increased risk of Serotonin Syndrome with the following symptoms: restlessness, diarrhea, fast heart beat, incoordination, nausea, vomiting. If it is so consult with your healthcare provider.