VITAMIN E TPGS, NF GRADE

9002-96-4N Interactive image ChEMBL2355578 64498Y DB11635 618-345-6 9938056 O03S90U1F2Y DTXSID90872278 DTXSID1048623, DTXSID90872278 InChI=1S/C35H58O6/c1-24(2)12-9-13-25(3)14-10-15-26(4)16-11-20-35(8)21-19-30-29(7)33(27(5)28(6)34(30)41-35)40-32(38)18-17-31(37)39-23-22-36/h24-26,36H,9-23H2,1-8H3YKey: AOBORMOPSGHCAX-UHFFFAOYSA-NYInChI=1/C35H58O6/c1-24(2)12-9-13-25(3)14-10-15-26(4)16-11-20-35(8)21-19-30-29(7)33(27(5)28(6)34(30)41-35)40-32(38)18-17-31(37)39-23-22-36/h24-26,36H,9-23H2,1-8H3Key: AOBORMOPSGHCAX-UHFFFAOYAU O=C(​‍​​​​​‍​‍‍‍‍​‍‍OCCO)CCC(=O)Oc2c(c(c1OC(CCc1c2C)(C)CCCC(C)CCCC(C)CCCC(C)C)C)C EUEMA:by INN UK:POM(Prescription only)EU:Rx-only DB11635 D06174 DTXSID90872278 DTXSID1048623, DTXSID90872278 Tocofersolan(INN; also known astocophersolan,tocopherolpolyethylene glycol succinate, orTPGS) is a synthetic water-soluble version ofvitamin E. Natural forms of vitamin E are fat soluble, but not water-soluble. Tocofersolan is apolyethylene glycol(PEG) derivative ofα-tocopherolsuccinate. The addition of PEG enables water solubility. Tocofersolan is used as a vitamin E supplement or to treat vitamin E deficiency in individuals who cannot absorb fats due to disease.On 24 July 2009 theEuropean Medicines Agencyapproved tocofersolan under the trade nameVedrop50 mg/ml oral solution for the treatment of vitamin E deficiency due to digestivemalabsorptioninpaediatricpatients withcongenitalor hereditary chroniccholestasis, from birth (in term newborns) to 16 or 18 years of age (depending on the region). Tocofersolan is also used in cosmetics and pharmaceuticals as anantioxidant.