Caspofungin inhibits the synthesis of beta-(1,3)-D-glucan, an essential component of the cell wall of Aspergillus species and Candida species.
Beta-(1,3)-D-glucan is not present in mammalian cells.
The primary target is beta-(1,3)-glucan synthase.
⚠️ Warnings
Pregnancy
Pregnancy:
Caspofungin should not be used during pregnancy unless strictly necessary.
Breastfeeding
Breastfeeding:
It is not known whether caspofungin is excreted in human breast milk. Available pharmacodynamic/toxicological data in animals have shown excretion of caspofungin in milk. Women receiving caspofungin should not breastfeed.
It is very important that your doctor monitors your or your child's progress while taking caspofungin to ensure the medicine is working properly.
Blood tests may be needed to check for unwanted effects.
You should immediately contact your doctor if you or your child experience any symptoms of liver problems, including dark-colored urine or pale stools, nausea, vomiting, loss of appetite, upper stomach pain, or yellowing of the skin or the whites of the eyes.
Caspofungin may cause a serious type of allergic reaction called anaphylaxis.
Anaphylaxis can be life-threatening and requires immediate medical attention.
You should immediately contact your doctor if you or your child develop a skin rash, itching, hoarseness, difficulty breathing, difficulty swallowing, or any swelling of the hands, face, or mouth after receiving caspofungin.
Do not take any other medicines that have not been discussed with your doctor.
This includes prescription and over-the-counter (OTC) medicines, as well as herbal or vitamin supplements.
