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ATC Code
J01MA09
Source
TFDA
J01MA09(WHO)
US:℞-only
5-Amino-1-cyclopropyl-7-[(3R,5S)3,5-dimethylpiperazin-1-yl]-6,8-difluoro-4-oxo-quinoline-3-carboxylic acid
110871-86-8Y
60464
DB01208Y
54517Y
Q90AGA787L
D00590Y
CHEBI:9212Y
ChEMBL850Y
DTXSID9023590
Interactive image
C[C@@H]1CN(C[C@@H](N1)C)c2c(c(c3c(c2F)n(cc(c3=O)C(=O)O)C4CC4)N)F
InChI=1S/C19H22F2N4O3/c1-8-5-24(6-9(2)23-8)17-13(20)15(22)12-16(14(17)21)25(10-3-4-10)7-11(18(12)26)19(27)28/h7-10,23H,3-6,22H2,1-2H3,(H,27,28)/t8-,9+YKey:DZZWHBIBMUVIIW-DTORHVGOSA-NY
Sparfloxacinis afluoroquinoloneantibioticused in the treatment of bacterial infections. It has a controversial safety profile.
It was patented in 1985 and approved for medical use in 1993.Zagam is no longer available in the United States.
⚠️ Warnings
• Caution should be exercised in patients with history of kidney, liver, or heart disease, epilepsy, G6PD deficiency, myasthenia gravis, slow heart rate, electrolyte disturbances, who are taking other medications, during pregnancy and breastfeeding.
• Avoid exposure to strong sunlight.
• Drink adequate fluid to reduce risk of crystalluria (presence of crystals in urine).