SERZONE TABLETS 250MG

C N06AX06(WHO) AU:S4(Prescription only)BR:Class C1(Other controlled substances)US:℞-onlyIn general: ℞ (Prescription only) 1-(3-[4-(3-chlorophenyl)piperazin-1-yl]propyl)-3-ethyl-4-(2-phenoxyethyl)-1H-1,2,4-triazol-5(4H)-one 83366-66-9Y82752-99-6 (hydrochloride) 4449 7247 DB01149Y 4294Y 59H4FCV1TF D08257Y CHEBI:7494Y ChEMBL623Y DTXSID2023357 Interactive image Clc4cccc(N3CCN(CCCN1/N=C(\N(C1=O)CCOc2ccccc2)CC)CC3)c4 InChI=1S/C25H32ClN5O2/c1-2-24-27-31(25(32)30(24)18-19-33-23-10-4-3-5-11-23)13-7-12-28-14-16-29(17-15-28)22-9-6-8-21(26)20-22/h3-6,8-11,20H,2,7,12-19H2,1H3YKey:VRBKIVRKKCLPHA-UHFFFAOYSA-NY Nefazodone, sold formerly under the brand namesSerzone,Dutonin, andNefadaramong others, is anatypical antidepressantmedication which is used in the treatment ofdepressionand for other uses.Nefazodone was withdrawn in most countries by 2004(due to liver toxicity).‍‍‍‍‍‍​​​‍​​​​​​ On December 2021, it was published that despite shortage it is still available in the United States.As of February 2026 it is available in the United States in generic form. The medication is takenby mouth. Side effectsof nefazodone includedry mouth,sleepiness,nausea,dizziness,blurred vision,weakness,lightheadedness,confusion, andpostural low blood pressure, among others.Rarely, nefazodone can cause seriousliver damage, with an incidence of death orliver transplantationof about 1 in every 250,000 to 300,000 patient years.Nefazodone is aphenylpiperazinecompoundand is related totrazodone. It has been described as aserotonin antagonist and reuptake inhibitor(SARI) due to its combined actions as apotentantagonistof theserotonin5-HT2Aand5-HT2Creceptorsand weakserotonin–norepinephrine–dopamine reuptake inhibitor(SNDRI). Nefazodone was introduced for medical use in 1994.Generic versionswere introduced in 2003.Serious liver toxicity was first reported with nefazodone in 1998, and it was withdrawn from most markets by 2004.However, as of 2023, it continues to be available in the United States in generic from one manufacturer,Teva Pharmaceuticals[failed verification]and is manufactured in Israel.