THILOCOMBIN TABLETS

C10AD05(WHO)C04AC02(WHO) (Pyridin-3-yl)methanol 100-55-0Y 7510 7229N 9TF312056Y CHEBI:45213 DTXSID6023367 Interactive image OCc1cccnc1 InChI=1S/C6H7NO/c8-5-6-2-1-3-7-4-6/h1-4,8H,5H2N Nicotinyl alcohol(pyridylcarbinol) is aniacinderivative used as ahypolipidemic agentand as avasodilator.​‍​​​​​‍​‍‍‍‍​‍‍ It causes flushing and may decrease blood pressure. It appears as a crystal that dissolves in water and alcohol with ease, also soluble in ether; melting range 147–148 °C. Nicotinic acidis a brief peripheral vasodilator; this compound was made to make its action longer and effective. It provokes cutaneous flushing in head and upper thorax with heat, but with no major effects in blood pressure. It is used in peripheral vascular diseases, likearteriosclerosis obliterans,Raynaud's disease,thromboangiitis obliterans (Buerger's disease),arterial embolism,chilblainsor migraine associated with vascular spasm. Fischer and Tebrock worked with this drug in more than two hundred patients for more than three years, achieving effective improvements, mainly in symptoms related tointermittent claudication,ulcer healing and others.