Nafcillin sodium

J01CF06(WHO) In general: ℞ (Prescription only) (2S,5R,6R)-6-[(2-ethoxy-1-naphthoyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 985-16-0Y 8982 DB00607Y 8634Y SY07234TTS CHEBI:7447Y ChEMBL1443Y DTXSID8023343 Interactive image O=C(O)[C@@H]3N4C(=O)[C@@H](NC(=O)c2c1ccccc1ccc2OCC)[C@H]4SC3(C)C InChI=1S/C21H22N2O5S/c1-4-28-13-10-9-11-7-5-6-8-12(11)14(13)17(24)22-15-18(25)23-16(20(26)27)21(2,3)29-19(15)23/h5-10,15-16,19H,4H2,1-3H3,(H,22,24)(H,26,27)/t15-,16+,19-/m1/s1YKey:GPXLMGHLHQJAGZ-JTDSTZFVSA-NY Nafcillin sodiumis anarrow-spectrum,second-generationbeta-lactam antibioticof thepenicillinclass. As abeta-lactamase-resistant penicillin, it is used to treatinfectionscaused byGram-positive bacteria, in particular,speciesofstaphylococcithat areresistantto other penicillins. Nafcillin is considered therapeutically equivalent tooxacillin, although one retrospective study found greater rates ofhypokalemiaandacute kidney injuryin patients taking nafcillin compared to patients taking oxacillin.