Enoxaparin is an antithrombotic agent belonging to the low-molecular-weight heparin group, used for the prevention and treatment of thromboembolic disorders. Its effects are primarily based on binding to antithrombin III, which inhibits coagulation factor Xa. This results in reduced formation of fibrin from fibrinogen. The medicinal product is usually administered subcutaneously. The most common possible adverse effects include haemorrhage.
Enoxaparin (ATC B01AB05) has antithrombotic and thrombolytic properties. Its effects are based on the binding and activation of antithrombin III. Antithrombin III in turn inactivates coagulation factor Xa. This results in reduced formation of fibrin from fibrinogen. Unlike standard heparin, factor IIa (thrombin) is inhibited to a lesser extent, and enoxaparin has a longer half-life.
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