Cefazolin Sandoz 2 g i.v., powder for infusion solution

( ARTG ) INDICATIONS: Treatment of the following serious infections due to susceptible organisms: Respiratory tract infections due to Strep. pneumoniae, Klebsiella sp., H. influenzae, Staph. aureus (penicillin sensitive and penicillin resistant) and group A beta-haemolytic streptococci. Injectable benzathine penicillin is considered to be the drug of choice in the treatment and prevention of streptococcal infections, including the prophylaxis of rheumatic fever. Cephazolin is effective in the eradication of streptococci from the nasopharynx; however, substantial data establishing the efficacy of cephazolin in the subsequent prevention of rheumatic fever are not available at present. Genitourinary tract infections due to E. coli, P. mirabilis, and klebsiella sp and some strains of enterobacter and enterococci. Skin and skin structure infections due to Staph. aureus (penicillin sensitive and penicillin resisant) and group A beta-haemolytic streptococci and other strains of streptococci. Bone and joint infections due to Staph. aureus. Septicaemia due to Strep. pneumoniae, Staph. aureus (penicillin sensitive and penicillin resistant), E. coli, P. mirabilis, and klebsiella sp. Endocarditis due to Staph. aureus (penicillin sensitive and penicillin resistant) and group A beta-haemolytic streptococci. Appropriate culture and susceptibility studies should be preformed to determine susceptibility of the causative organism to cephazolin.