What is Daurismo used for?

1 INDICATIONS AND USAGE DAURISMO is indicated, in combination with low-dose cytarabine, for the treatment of newly-diagnosed acute myeloid leukemia (AML) in adult patients who are ≥75 years old or who have comorbidities that preclude use of intensive induction chemotherapy. DAURISMO is a hedgehog pathway inhibitor indicated, in combination with low-dose cytarabine, for the treatment of newly-diagnosed acute myeloid leukemia (AML) in adult patients who are ≥75 years old or who have comorbidities

How does Daurismo work?

11 DESCRIPTION DAURISMO (glasdegib) is a hedgehog pathway inhibitor.

What pharmaceutical form is Daurismo available in?

Daurismo: Tabletki powlekane 25 mg (doustna)

Is Daurismo OTC or prescription only?

Daurismo requires a doctor's prescription.

What are the side effects of Daurismo?

6 ADVERSE REACTIONS The following clinically-significant adverse reactions are described elsewhere in the labeling: • QTc Interval Prolongation [see Warnings and Precautions (5.2) ] • Musculoskeletal Adverse Reactions [see Warnings and Precautions (5.3) ] Most common adverse reactions (incidence ≥20%) are anemia, fatigue, hemorrhage, febrile neutropenia, musculoskeletal pain, nausea, edema, thrombocytopenia, dyspnea, decreased appetite, dysgeusia, mucositis, constipation, and rash. ( 6.1 ) To re

Who should NOT take Daurismo?

4 CONTRAINDICATIONS None. None. ( 4 )

Does Daurismo interact with other medications?

7 DRUG INTERACTIONS Table 5. Drug Interactions with DAURISMO Strong CYP3A Inhibitors Clinical Impact • Co-administration of DAURISMO with strong CYP3A inhibitors increased glasdegib plasma concentrations [see Clinical Pharmacology (12.3) ]. • Increased glasdegib concentrations may increase the risk of adverse reactions including QTc interval prolongation [see Warnings and Precautions (5.2) ] . Prevention or Management • Consider alternative therapies that are not strong CYP3A4 inhibitors during

Can Daurismo be used during pregnancy?

8 USE IN SPECIFIC POPULATIONS Lactation: Advise women not to breastfeed. ( 8.2 ) 8.1 Pregnancy Risk Summary Based on its mechanism of action and findings in animal embryo-fetal developmental toxicity studies, DAURISMO can cause fetal harm when administered to a pregnant woman [see Clinical Pharmacology (12.1) ] . There are no clinical data on the use of DAURISMO in pregnant women to inform of a drug-associated risk of major birth defects and miscarriage. DAURISMO is not recommended for use durin

What precautions should be taken with Daurismo?

Any unused medicinal product or waste material should be disposed of in accordance with local requirements.

What ATC class does Daurismo belong to?

Daurismo: ATC L01XJ03. ATC is the WHO Anatomical Therapeutic Chemical classification — it groups drugs by organ system and pharmacological mechanism.

Daurismo

25 mg, Tabletki powlekane

INN: Glasdegibum

Data updated: 2026-04-13

Available in:

🇨🇿🇩🇪🇬🇧🇫🇷🇵🇱🇵🇹🇸🇰🇺🇦

Form

Tabletki powlekane

Dosage

25 mg

Route

doustna

Storage

Store at 20°C to 25°C (68°F to 77°F); excursions permitted between 15°C to 30°C (59°F to 86°F).

User Reviews

Reviews reflect personal experiences and are not medical advice. Always consult your doctor.