Pharmacotherapeutic group: Antipruritics, including antihistamines, anaesthetics, etc. Antihistamines for topical use.
ATC code: D04AA13
Mechanism of action and pharmacodynamic effects
Dimetindene maleate is a histamine H1-receptor antagonist with high binding affinity for these receptors. It therefore markedly reduces capillary hyperpermeability associated with immediate hypersensitivity reactions. When applied topically, dimetindene maleate also exhibits local anaesthetic activity.
Dimetindene maleate counteracts pruritus of various aetiologies and rapidly relieves itching and irritation. The lubricating base facilitates penetration of the active substance into the skin.
⚠️ Warnings
This product is intended for short-term use. If symptoms worsen or fail to improve within 3 days, the patient should consult a physician.
In cases of severe pruritus or involvement of a large skin area, the patient should seek medical advice to consider adjunctive systemic therapy with oral dimetindene maleate.
When a larger skin area is treated, it must not be exposed to sunlight for prolonged periods.
In infants and young children, the product should not be applied to extensive skin areas, particularly where open or inflamed lesions are present.
Contact with the eyes and mucous membranes should be avoided during use.
Information on excipients
Beldimet contains benzalkonium chloride, which may cause skin irritation.
Benzalkonium chloride is not expected to be associated with harmful effects in the mother during pregnancy and breast-feeding, as its cutaneous absorption is minimal.
This product is not intended for application to mucous membranes.
Beldimet contains propylene glycol, which may cause skin irritation.
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