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( ARTG ) Malaria treatment: LARIAM is indicated for the treatment of acute attacks of malaria due to P.falciparum infection resistant to conventional antimalarial drugs.‍‍‍‍‍‍​​​‍​​​​​​ Following therapy of mixed P.falciparum/P.vivax malaria with LARIAM relapse prophylaxis with an 8-aminoquinoline derivative (e.g. primaquine) should be considered in order to eliminate liver forms of P.vivax. Malaria Prophylaxis: For travellers to countries with documented chloroquine and antifolate combination ( [sulfadoxine/pyrimethamine] / [dapsone/pyrimethamine] ) resistant P.falciparum malaria, who are considered to be at high risk for malaria in view of their residence or travel (of up to 3 months duration) through rural areas (between the dusk to dawn period). For travellers hypersensitive to sulphonamides and sulphones, who are considered to be at high risk for malaria in view of their residence or travel (of up to 3 months duration) through rural areas, (between the dusk to dawn period) in countries with high level chloroquine-resistant P.falciparum malaria.