Reviews reflect personal experiences and are not medical advice. Always consult your doctor.
(FR)
Source
BDPM_FR
USDailyMed:Mefloquine
AU:B3
P01BC02(WHO)
AU:S4(Prescription only)CA:℞-onlyUK:POM(Prescription only)US:℞-only
[(R*,S*)-2,8-Bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanol
53230-10-7Y
40692
DB00358Y
37171Y
TML814419R
D04895Y
ChEMBL416956N
005218
DTXSID50860636
Interactive image
FC(F)(F)c2cccc1c(cc(nc12)C(F)(F)F)[C@H](O)[C@@H]3NCCCC3
InChI=1S/C17H16F6N2O/c18-16(19,20)11-5-3-4-9-10(15(26)12-6-1-2-7-24-12)8-13(17(21,22)23)25-14(9)11/h3-5,8,12,15,24,26H,1-2,6-7H2/t12-,15+/m1/s1YKey:XEEQGYMUWCZPDN-DOMZBBRYSA-NY
Mefloquine, sold under the brand nameLariamamong others, is amedicationused to prevent or treatmalaria.When used for prevention it is typically started before potential exposure and continued for several weeks after potential exposure.It can be used to treat mild or moderate malaria but is not recommended for severe malaria.It is takenby mouth.
Common side effects include vomiting, diarrhea, headaches, sleep disorders, and a rash.Serious side effects include potentially long-term mental health problems such asdepression,hallucinations, andanxietyand neurological side effects such aspoor balance,seizures, andringing in the ears.It is therefore not recommended in people with a history of mental health problems orepilepsy.It appears to be safe duringpregnancyandbreastfeeding.
Mefloquine was developed by the United States Army in the 1970s and came into use in the mid-1980s.It is on theWorld Health Organization's List of Essential Medicines.It is available as ageneric medication.