What is Benfluorex hydrochloride used for?

Metformin iscontraindicatedin people with: Severe renal impairment (estimatedglomerular filtration rate(eGFR) below 30 mL/min/1.73 m2)Known hypersensitivity to metforminAcute or chronicmetabolic acidosis, includingdiabetic ketoacidosis(from uncontrolled diabetes),with or withoutcoma

What are the side effects of Benfluorex hydrochloride?

The most commonadverse effectof metformin is gastrointestinal irritation, includingdiarrhea, cramps, nausea, vomiting, and increasedflatulence.Metformin is more commonly associated with gastrointestinal adverse effects than most other antidiabetic medications.The most serious potential adverse effect of metformin islactic acidosis; this complication is rare, and seems to be related to impaired liver or kidney function.Metformin is not approved for use in those with severe kidne

Does Benfluorex hydrochloride interact with other medications?

TheH2-receptor antagonistcimetidinecauses an increase in the plasma concentration of metformin by reducingclearanceof metformin by the kidneys;both metformin and cimetidine are cleared from the body bytubular secretion, and both, particularly thecationic(positivelycharged) form of cimetidine, may compete for the same transport mechanism.A smalldouble-blind, randomized study found theantibioticcephalexinto also increase metformin concentrations by a similar mechanism;theoretical

Can Benfluorex hydrochloride be used during pregnancy?

A total review of metformin use during pregnancy compared toinsulinalone found good short-term safety for both the mother and baby, but safety in the longer term is unclear.Severalobservational studiesand randomized controlled trials found metformin to be as effective and safe as insulin for the management of gestational diabetes.Nonetheless, several concerns have been raised and evidence on the long-term safety of metformin for both mother and child is lacking.Compared with insulin, women wi

What ATC class does Benfluorex hydrochloride belong to?

Benfluorex hydrochloride: ATC A10BX06. ATC is the WHO Anatomical Therapeutic Chemical classification — it groups drugs by organ system and pharmacological mechanism.

Benfluorex hydrochloride

This information is for educational purposes only. It is not intended as medical advice. Always consult a qualified healthcare professional.

USDailyMed:Metformin AU:C A10BA02(WHO) Combinations:Metformin and sulfonylureasA10BD02(WHO)Metformin and rosiglitazoneA10BD03(WHO)Metformin and pioglitazoneA10BD05(WHO)Metformin and sitagliptinA10BD07(WHO)Metformin and vildagliptinA10BD08(WHO)Metformin and saxagliptinA10BD10(WHO)Metformin and linagliptinA10BD11(WHO)Metformin and alogliptinA10BD13(WHO)Metformin and repaglinideA10BD14(WHO)Metformin and dapagliflozinA10BD15(WHO)Metformin and canagliflozinA10BD16(WHO)Metformin and acarboseA10BD17(WHO)Metformin and gemigliptinA10BD18(WHO)Metformin and empagliflozinA10BD20(WHO)Metformin and evogliptinA10BD22(WHO)Metformin and ertugliflozinA10BD23(WHO)Metformin, saxagliptin, and dapagliflozinA10BD25(WHO)Metformin and lobeglitazoneA10BD26(WHO)Metformin, linagliptin and empagliflozinA10BD27(WHO)Metformin and teneligliptinA10BD28(WHO) Metformin and sulfonylureasA10BD02(WHO)Metformin and rosiglitazoneA10BD03(WHO)Metformin and pioglitazoneA10BD05(WHO)Metformin and sitagliptinA10BD07(WHO)Metformin and vildagliptinA10BD08(WHO)Metformin and saxagliptinA10BD10(WHO)Metformin and linagliptinA10BD11(WHO)Metformin and alogliptinA10BD13(WHO)Metformin and repaglinideA10BD14(WHO)Metformin and dapagliflozinA10BD15(WHO)Metformin and canagliflozinA10BD16(‍‍‍‍‍‍‍‍‍‍‍‍‍WHO)Metformin and acarboseA10BD17(WHO)Metformin and gemigliptinA10BD18(WHO)Metformin and empagliflozinA10BD20(WHO)Metformin and evogliptinA10BD22(WHO)Metformin and ertugliflozinA10BD23(WHO)Metformin, saxagliptin, and dapagliflozinA10BD25(WHO)Metformin and lobeglitazoneA10BD26(WHO)Metformin, linagliptin and empagliflozinA10BD27(WHO)Metformin and teneligliptinA10BD28(WHO) AU:S4(Prescription only)CA:℞-onlyUK:POM(Prescription only)US:℞-onlyEU:Rx-only N,N-Dimethylimidodicarbonimidic diamide 657-24-9as HCl:1115-70-4 4091as HCl:14219 4779 DB00331as HCl:DBSALT000114 3949as HCl:13583 9100L32L2Nas HCl:786Z46389E D04966as HCl:D00944 CHEBI:6801as HCl:CHEBI:6802 ChEMBL1431as HCl:ChEMBL1703 DTXSID2023270 Interactive imageas HCl:Interactive image CN(C)C(=N)N=C(N)Nas HCl: Cl.CN(C)C(=N)NC(N)=N InChI=1S/C4H11N5/c1-9(2)4(7)8-3(5)6/h1-2H3,(H5,5,6,7,8)Key:XZWYZXLIPXDOLR-UHFFFAOYSA-Nas HCl: InChI=1S/C4H11N5.ClH/c1-9(2)4(7)8-3(5)6;/h1-2H3,(H5,5,6,7,8);1HKey:OETHQSJEHLVLGH-UHFFFAOYSA-N Metformin, sold under the brand nameGlucophage, among others, is the mainfirst-line medicationfor the treatment oftype2 diabetes,particularly in people who areoverweight.It is also used in the treatment ofpolycystic ovary syndrome,and is sometimes used as anoff-label adjunctto lessen the risk ofmetabolic syndromein people who takeantipsychoticmedication.It has been shown toinhibit inflammation,and is not associated withweight gain.Metformin istaken by mouth. Metformin is generally well tolerated.Common adverse effects includediarrhea,nausea, andabdominal pain.It has a small risk of causinglow blood sugar.High blood lactic acid level(acidosis) is a concern if the medication is used in overly large doses or prescribed to people with severekidney problems. Metformin is abiguanideanti-hyperglycemicagent.It works by decreasingglucose productionin theliver, increasing theinsulinsensitivity of body tissues,and increasingGDF15secretion, which reduces appetite and caloric intake. Metformin was first described in the scientific literature in 1922 by Emil Werner and James Bell.French physician Jean Sterne began the study in humans in the 1950s.It was introduced as a medication in France in 1957.It is on theWorld Health Organization's List of Essential Medicines.It is available as ageneric medication.In 2023, it was the second most commonly prescribed medication in the United States, with more than 85million prescriptions.In Australia, it was one of the top 10 most prescribed medications between 2017 and 2023.

Benfluorex hydrochloride

User Reviews