Question 1

What is ÉTODOLAC used for?

Accepted Answer

NSAIDs are used for the management of mild to moderate pain, fever, andinflammation. They work by reducing the levels ofprostaglandins, which are chemicals that are responsible for pain and the fever and tenderness that occur with inflammation. Etodolac blocks thecyclooxygenase(abbrev. COX) enzymes which formprostanoids, resulting in lower concentrations ofprostaglandins. As a consequence, inflammation, pain and fever are reduced.
Etodolac is 179 times more selective at blocking COX-2 than COX-1

Question 2

How does ÉTODOLAC work?

Accepted Answer

M01AB08(WHO)
AU:S4(Prescription only)UK:POM(Prescription only)US:℞-only
(RS)-2-(1,8-Diethyl-4,9-dihydro-3H-pyrano[3,4-b]indol-1-yl)acetic acid
41340-25-4Y
3308
7185
DB00749Y
3192Y
2M36281008
D00315Y
CHEBI:4909Y
ChEMBL622Y
DTXSID9020615
Interactive image
CCc2cccc3c1CCOC(CC)(CC(=O)O)c1[nH]c23
InChI=1S/C17H21NO3/c1-3-11-6-5-7-12-13-8-9-21-17(4-2,10-14(19)20)16(13)18-15(11)12/h5-7,18H,3-4,8-10H2,1-2H3

Question 3

Does ÉTODOLAC interact with other medications?

Accepted Answer

Etodolac should be avoided by patients with a history ofasthmaattacks,hives, or otherallergic reactionstoaspirinor other NSAIDs.  Rare but severe allergic reactions have been reported in such individuals.  It also should be avoided by patients withpeptic ulcerdisease or poorkidney function, since this medication can worsen both conditions.  Etodolac is used with caution in patients taking blood thinning medications (anticoagulants), such aswarfarin(Coumadin), because it increases the risk ofblee

Question 4

Can ÉTODOLAC be used during pregnancy?

Accepted Answer

Etodolac is generally avoided duringpregnancyandnursing. NSAIDs may cause adverse cardiovascular effects in thefetusduring pregnancy.
In October 2020, the U.S.Food and Drug Administration(FDA) required theprescribing informationto be updated for all nonsteroidal anti-inflammatory medications to describe the risk of kidney problems in unborn babies that result in low amniotic fluid.They recommend avoiding NSAIDs in pregnant women at 20 weeks or later in pregnancy.

Question 5

Who manufactures ÉTODOLAC?

Accepted Answer

LABORATOIRES ETHYPHARM (FR)

ÉTODOLAC

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