LORAZEPAM VIATRIS 1 mg, comprimé pelliculé sécable

USDailyMed:Lorazepam AU:C N05BA06(WHO) AU:S4(Prescription only)BR:Class B1(Psychoactive drugs)CA:Schedule IVDE: Prescription only (Anlage IIIfor higher doses)UK:POM(Prescription only)US:Schedule IVSE: Förteckning IV IVTooltip Intravenous therapy: 1–5 minutesIMTooltip Intramuscular injection: 15–30 minutesPOTooltip Oral administration: 20–30 minutes IV/IM: 12–24 hoursPO: 6–8 hours (RS)-7-Chloro-5-(2-chlorophenyl)-3-hydroxy-1,3-dihydro-1,4-benzodiazepin-2-one 846-49-1Y 3958 DB00186N 3821Y O26FZP769L D00365Y CHEBI:6539 ChEMBL580Y DTXSID7023225 Interactive image O=C1Nc2ccc(Cl)cc2C(c2ccccc2Cl)=NC1O InChI=1S/C15H10Cl2N2O2/c16-8-5-6-12-10(7-8)13(19-15(21)14(20)18-12)9-3-1-2-4-11(9)17/h1-7,15,21H,(H,18,20)YKey:DIWRORZWFLOCLC-UHFFFAOYSA-NY Lorazepam, sold under the brand nameAtivanamong others, is abenzodiazepinemedication.It is used to trea​​​‍​​‍​​​​‍​​‍‍tanxiety(includinganxiety disorders),insomnia,severe agitation, activeseizuresincludingstatus epilepticus,alcohol withdrawal, andchemotherapy-induced nausea and vomiting.It is also used during surgery tointerfere with memory formation, tosedatethose who are beingmechanically ventilated, and, along with other treatments, foracute coronary syndromedue tococaineuse.It can be givenorally(by mouth),transdermally(on the skin via a topical gel or patch),intravenously(injection into a vein), orintramuscularly(injection into a muscle).When given by injection, onset of effects is between one and thirty minutes and effects last for up to a day. Common side effects includeweakness,sleepiness,dizziness,decreased alertness,decreased memory formation,low blood pressure, and adecreased effort to breathe.When given intravenously, the person is typically closely monitored.Among those who aredepressed, there may be an increased risk ofsuicide.With long-term use,tolerancemay develop, with larger doses required for the same effect.Physical dependenceandpsychological dependencemay also occur.If stopped suddenly after long-term use,benzodiazepine withdrawal syndromemay occur.Older people more often develop adverse effects.In this age group, lorazepam is associated with falls andhip fractures.Due to these concerns, lorazepam use is generally recommended for up to four weeks. Lorazepam was initially patented in 1963 and went on sale in the United States in 1977.It is on theWorld Health Organization's List of Essential Medicines.It is available as ageneric medication.In 2023, it was the 100th most commonly prescribed medication in the United States, with more than 6million prescriptions.