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NOVARTIS EUROPHARM (IRLANDE) (FR)
Source
BDPM_FR
174.96669±0.00005174.97±0.01(abridged)
1st: 523.5 kJ/mol2nd: 1340 kJ/mol3rd: 2022.3 kJ/mol
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Lutetiumis achemical element; it hassymbolLuandatomic number71. It is a silvery whitemetal, which resists corrosion in dry air, but not in moist air. Lutetium is the last element in thelanthanideseries, and it is traditionally counted among therare earth elements; it can also be classified as the first element of the sixth-periodtransition metals.
Lutetium was independently discovered in 1907 by French scientistGeorges Urbain, Austrian mineralogistBaronCarl Auer von Welsbach, and American chemistCharles James.All of these researchers found lutetium as an impurity inytterbium. The dispute on the priority of the discovery occurred shortly after, with Urbain and Welsbach accusing each other of publishing results influenced by the published research of the other; the naming honor went to Urbain, as he had published his results earlier. He chose the nameluteciumfor the new element honoring the Latin name for Paris,Lutetia.In 1949 the spelling was changed tolutetium. In 1909, the priority was finally granted to Urbain and his names were adopted as official ones; however, the namecassiopeium(or latercassiopium) for element 71 proposed by Welsbach was used by many German scientists until the 1950s.
Lutetium is not a particularly abundant element, although it is significantly more common thansilverin the Earth's crust. It has few specific uses. Lutetium-176 is a relatively abundant (2.5%) radioactive isotope with a half-life of about 38 billion years, used todetermine the ageof minerals andmeteorites. Lutetium usually occurs in association with the elementyttriumand is sometimes used in metalalloysand as acatalystin various chemical reactions.177Lu-DOTA-TATEis used forradionuclide therapy(seeNuclear medicine) on neuroendocrine tumours. Lutetium has the highestBrinell hardnessof any lanthanide, at 890–1300MPa.
⚠️ Warnings
Like other rare-earth metals, lutetium is regarded as having a low degree of toxicity, but its compounds should be handled with care nonetheless: for example, lutetium fluoride inhalation is dangerous and the compound irritates skin.Lutetium nitrate may be dangerous as it may explode and burn once heated. Lutetium oxide powder is toxic as well if inhaled or ingested.
Similarly to the other rare-earth metals, lutetium has no known biological role, but it is found even in humans, concentrating in bones, and to a lesser extent in the liver and kidneys.Lutetium salts are known to occur together with other lanthanide salts in nature; the element is the least abundant in the human body of all lanthanides.Human diets have not been monitored for lutetium content, so it is not known how much the average human takes in, but estimations show the amount is only about several micrograms per year, all coming from tiny amounts absorbed by plants. Soluble lutetium salts are mildly toxic, but insoluble ones are not.
