ALEUDRINA

AU:A C01CA02(WHO)R03AB02(WHO)R03CB01(WHO) AU:S4(Prescription only)In general: ℞ (Prescription only) 4-[1-hydroxy-2-(isopropylamino)ethyl]benzene-1,2-diol 7683-59-2Y 3779 536 DB01064Y 3647Y L628TT009W D08090Y ChEMBL434Y DTXSID4023175 Interactive image CC(C)NCC(O)c1cc(O)c(O)cc1 InChI=1S/C11H17NO3/c1-7(2)12-6-11(15)8-3-4-9(13)10(14)5-8/h3-5,7,11-15H,6H2,1-2H3YKey:JWZZKOKVBUJMES-UHFFFAOYSA-NY Isoprenaline, also known asisoproterenoland sold under the brand nameIsuprelamong others, is asympathomimeticmedicationwhich is used in the treatment of acutebradycardia(slow heart rate),heart block, and rarely forasthma, among other indications.It is used byinjection into a vein,muscle,fat, or theheart, byinhalation, and in the pastunder the tongueorinto the rectum. Side effects of isoprenaline includerapid heart beat,heart palpitations, andarrhythmias, among others.Isoprenaline is aselectiveagonistof theβ-adrenergic receptors, including both theβ1-andβ2-adrenergic receptors.By activating thesereceptors, it increasesheart rateand theforce of heart contractions.Chemically, isoprenaline is asyntheticcatecholamineand is theN-isopropylanalogueofnorepinephrine(noradrenaline) andepinephrine(adrenaline). Isoprenaline was one of the firstsyntheticsympathomimeticaminesand was the firstselectiveβ-adrenergic receptoragonist.The medication was discovered in 1940and was introduced for medical use in 1947.