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About This Product
Manufacturer
Viatris Limited (ES)
ATC Code
N02CC05
Source
CIMA_ES
USDailyMed:Ziprasidone
AU:C
N05AE04(WHO)
AU:S4(Prescription only)BR:Class C1(Other controlled substances)US:℞-only
5-{2-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]ethyl}-6-chloro-1,3-dihydro-2H-indol-2-one
146939-27-7Y
60854
59
DB00246Y
54841Y
6UKA5VEJ6X
D08687Y
CHEBI:10119Y
ChEMBL708Y
DTXSID4023753
Interactive image
O=C1Cc2c(N1)cc(Cl)c(c2)CCN3CCN(CC3)c4nsc5ccccc45
InChI=1S/C21H21ClN4OS/c22-17-13-18-15(12-20(27)23-18)11-14(17)5-6-25-7-9-26(10-8-25)21-16-3-1-2-4-19(16)28-24-21/h1-4,11,13H,5-10,12H2,(H,23,27)YKey:MVWVFYHBGMAFLY-UHFFFAOYSA-NY
Ziprasidone, sold under the brand nameGeodonamong others, is anatypical antipsychoticused to treatschizophreniaandbipolar disorder.It may be usedby mouthand byinjection into a muscle(IM).The intramuscular form may be used for acuteagitationin people with schizophrenia.
Common side effects includetremors,tics,dizziness,dry mouth,restlessness,nausea, and mildsedation.Although it can also causeweight gain, the risk is much lower than for other atypical antipsychotics.How it works is not entirely clear but is believed to involve effects onserotoninanddopaminein thebrain.
Ziprasidone was approved for medical use in the United States in 2001.The pills are made up of the hydrochloride salt, ziprasidone hydrochloride. The intramuscular form is themesylate, ziprasidone mesylate trihydrate, and is provided as alyophilizedpowder. In 2020, it was the 282nd most commonly prescribed medication in the United States, with more than 1million prescriptions.
⚠️ Warnings
• Caution should be exercised in patients with history of hypersensitivity to sulfonamides, liver or kidney impairment, seizures; children, pregnancy and breastfeeding.
• It may significantly increase blood pressure. Monitor blood pressure level regularly.
• It may cause drowsiness, do not drive a car or operate machinery while taking this medication.
Patient may develop with increased risk of Serotonin Syndrome with the following symptoms: increased heart rate, shivering, sweating, dilated pupils,etc . If it is so consult with your healthcare provider.
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Verified by medical editor
Dr. Ozarchuk, PharmD · April 2026
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