What is Efavirenz used for?

1 INDICATIONS & USAGE Efavirenz in combination with other antiretroviral agents is indicated for the treatment of human immunodeficiency virus type 1 (HIV-1) infection in adults and in pediatric patients at least 3 months old and weighing at least 3.5 kg. Efavirenz is a non-nucleoside reverse transcriptase inhibitor indicated in combination with other antiretroviral agents for the treatment of human immunodeficiency virus type 1 infection in adults and in pediatric patients at least 3 months old

How does Efavirenz work?

11 DESCRIPTION Efavirenz, USP is an HIV-1 specific, non-nucleoside, reverse transcriptase inhibitor (NNRTI).

What pharmaceutical form is Efavirenz available in?

Efavirenz: Tabletki powlekane 600 mg (doustna)

Is Efavirenz OTC or prescription only?

Efavirenz requires a doctor's prescription.

What are the side effects of Efavirenz?

6 ADVERSE REACTIONS The most significant adverse reactions observed in patients treated with efavirenz are: •psychiatric symptoms [see Warnings and Precautions ( 5.5 )], •nervous system symptoms [see Warnings and Precautions ( 5.6 )], •rash [see Warnings and Precautions ( 5.8 )]. •hepatotoxicity [see Warnings and Precautions ( 5.9 )] Most common adverse reactions (>5%, moderate-severe) are impaired concentration, abnormal dreams, rash, dizziness, nausea, headache, fatigue, insomnia, and vomiting

Who should NOT take Efavirenz?

4 CONTRAINDICATIONS • Efavirenz is contraindicated in patients with previously demonstrated clinically significant hypersensitivity (e.g., Stevens-Johnson syndrome, erythema multiforme, or toxic skin eruptions) to any of the components of this product. • Coadministration of efavirenz with elbasvir and grazoprevir is contraindicated [ see Warnings and Precautions ( 5.1 ) and Drug Interactions ( 7.1 ) ]. •Patients with previously demonstrated hypersensitivity (e.g., Stevens-Johnson syndrome, eryth

Does Efavirenz interact with other medications?

7 DRUG INTERACTIONS Coadministration of efavirenz can alter the concentrations of other drugs and other drugs may alter the concentrations of efavirenz. The potential for drug-drug interactions should be considered before and during therapy. ( 7 ) 7.1 Potential for efavirenz to Affect other Drugs Efavirenz has been shown in vivo to induce CYP3A and CYP2B6. Other compounds that are substrates of CYP3A or CYP2B6 may have decreased plasma concentrations when coadministered with efavirenz 7.2 Potent

Can Efavirenz be used during pregnancy?

8 USE IN SPECIFIC POPULATIONS • Lactation : Breastfeeding not recommended. ( 8.2 ) • Females and Males of Reproductive Potential : Pregnancy testing and contraception are recommended. ( 8.3 ) • Hepatic impairment : Efavirenz is not recommended for patients with moderate or severe hepatic impairment. Use caution in patients with mild hepatic impairment. ( 8.6 ) • Pediatric patients : The incidence of rash was higher than in adults. ( 5.8 , 6.2 , 8.4 ) 8.1 Pregnancy Pregnancy Exposure Registry The

What precautions should be taken with Efavirenz?

Any unused product or waste material should be disposed of in accordance with local requirements.

What ATC class does Efavirenz belong to?

Efavirenz: ATC J05AG03. ATC is the WHO Anatomical Therapeutic Chemical classification — it groups drugs by organ system and pharmacological mechanism.

Efavirenz

600 mg, Tabletki powlekane

INN: Efavirenzum

Data updated: 2026-04-13

Available in:

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Form

Tabletki powlekane

Dosage

600 mg

Route

doustna

Storage

—

About This Product

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