Question 1

What is Elexacaftor, ivacaftor and tezacaftor used for?

Accepted Answer

This medication is a CF transmembrane conductance regulator agonist, prescribed for cystic fibrosis (CF) in patients more than 6 years old. It works by improving the function of a protein in the body to decrease the build-up of thick mucus in the lungs and improving other symptoms of cystic fibrosis.

Question 2

What is the active ingredient in Elexacaftor, ivacaftor and tezacaftor?

Accepted Answer

Elexacaftor, ivacaftor and tezacaftor

Question 3

What are the side effects of Elexacaftor, ivacaftor and tezacaftor?

Accepted Answer

Most Common
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Headache, upper respiratory tract infection, stomach (abdominal) pain, diarrhea, rash, nausea, and dizziness.

Question 4

Can Elexacaftor, ivacaftor and tezacaftor be used during pregnancy?

Accepted Answer

• Caution should be exercised in patients with history of liver or kidney problems, who are taking other medications, any allergy, during pregnancy and breastfeeding.
•  Avoid drinking grapefruit juice, or eat grapefruit or Seville oranges while taking this medication.
•  Always take it with fatty food.
•  It may cause dizziness, do not drive a car or operate machinery while taking this medication.

Question 5

What precautions should be taken with Elexacaftor, ivacaftor and tezacaftor?

Accepted Answer

• Caution should be exercised in patients with history of liver or kidney problems, who are taking other medications, any allergy, during pregnancy and breastfeeding.
•  Avoid drinking grapefruit juice, or eat grapefruit or Seville oranges while taking this medication.
•  Always take it with fatty food.
•  It may cause dizziness, do not drive a car or operate machinery while taking this medication.

Question 6

What ATC class does Elexacaftor, ivacaftor and tezacaftor belong to?

Accepted Answer

Elexacaftor, ivacaftor and tezacaftor: ATC R07AX02. ATC is the WHO Anatomical Therapeutic Chemical classification — it groups drugs by organ system and pharmacological mechanism.

Elexacaftor, ivacaftor and tezacaftor

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