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(ES)
Source
CIMA_ES
USDailyMed:Budesonide
AU:A/B3
A07EA06(WHO)D07AC09(WHO),R01AD05(WHO),R03BA02(WHO)
AU:S2(Pharmacy medicine) /S4CA:℞-onlyUK:POM(Prescription only)US:OTC/ Rx-onlyEU:Rx-only
11β,21-Dihydroxy-16α,17α-[butane-1,1-diylbis(oxy)]pregna-1,4-diene-3,20-dione
51333-22-3Y
40000
DB01222Y
4444479N
Q3OKS62Q6X
D00246Y
ChEMBL1370N
8W5 (PDBe,RCSB PDB)
DTXSID8020202
Interactive image
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InChI=1S/C25H34O6/c1-4-5-21-30-20-11-17-16-7-6-14-10-15(27)8-9-23(14,2)22(16)18(28)12-24(17,3)25(20,31-21)19(29)13-26/h8-10,16-18,20-22,26,28H,4-7,11-13H2,1-3H3/t16-,17-,18-,20+,21?,22+,23-,24-,25+/m0/s1NKey:VOVIALXJUBGFJZ-KWVAZRHASAN
Budesonide, sold under the brand namePulmicort, among others, is asteroid medication.It is available as aninhaler,nebulization solution,pill,nasal spray, andrectal foam.The inhaled form is used in the long-term management ofasthmaandchronic obstructive pulmonary disease(COPD).The nasal spray is used forallergic rhinitisandnasal polyps.Modified-release pills or capsulesand rectal forms may be used forinflammatory bowel diseaseincludingCrohn's disease,ulcerative colitis, andmicroscopic colitis.
Commonside effectswith the inhaled form includerespiratory infections, cough, and headaches.Common side effects with the pills include feeling tired, vomiting, andjoint pains.Serious side effects include an increased risk of infection, loss of bone strength, andcataracts.Long-term use of the pill form may causeadrenal insufficiency.Stopping the pills suddenly following long-term use may therefore be dangerous.The inhaled form is generally safe inpregnancy.Budesonide chiefly acts as aglucocorticoid.
Budesonide was initially patented in 1973.Commercial use as an asthma medication began in 1981.It is on theWorld Health Organization's List of Essential Medicines.Some forms are available as ageneric medication.In 2023, it was the 162nd most commonly prescribed medication in the United States, with more than 3million prescriptions.