NAVELBINE 10 mg/ml CONCENTRADO PARA SOLUCION PARA PERFUSION

AU:D L01CA04(WHO) AU:S4(Prescription only)CA:℞-onlyUK:POM(Prescription only)US:℞-only Methyl (2β,3β,4β,5α,12β,19α)-4-acetoxy-15-[(12S,14R)-16-ethyl-12-(methoxycarbonyl)-1,10-diazatetracyclo[12.3.1.03,11.04,9]octadeca-3(11),4,6,8,15-pentaen-12-yl]-3-hydroxy-16-methoxy-1-methyl-6,7-didehydroaspidospermidine-3-carboxylate 71486-22-1Y 5311497 DB00361Y 4470974Y Q6C979R91Y D08680Y ChEMBL607994N DTXSID8040640 Interactive image [H][C@]89C=C(CC)CN(Cc1c([nH]c2ccccc12)[C@@](C(=O)OC)(c3cc4c(cc3OC)N(C)[C@@]5([H])[C@@](O)(C(=O)OC)[C@H](OC(C)=O)[C@]7(CC)C=CCN6CC[C@]45[C@@]67[H])C8)C9 InChI=1S/C45H54N4O8/c1-8-27-19-28-22-44(40(51)55-6,36-30(25-48(23-27)24-28)29-13-10-11-14-33(29)46-36)32-20-31-34(21-35(32)54-5)47(4)38-43(31)16-18-49-17-12-15-42(9-2,37(43)49)39(57-26(3)50)45(38,53)41(52)56-7/h10-15,19-21,28,37-39,46,53H,8-9,16-18,22-25H2,1-7H3/t28-,37-,38+,39+,42+,43+,44-,45-/m0/s1YKey:GBABOYUKABKIAF-IELIFDKJSA-NY Vinorelbine, sold under the brand nameNavelbineamong others, is achemotherapy medicationused to treat a number of types of cancer.This includesbreast cancerandnon-small cell lung cancer.It is given byinjection into a veinor by mouth. Common side effects includebone marrow suppression, pain at the site of injection, vomiting, feeling tired, numbness, and diarrhea.Other serious side effects includeshortness of breath.Use duringpregnancymay harm the baby.Vinorelbine is in thevinca alkaloidfamily of medications.It is believed to work by disrupting the normal function ofmicrotubulesand thereby stoppingcell division. Vinorelbine was approved for medical use in the United States in 1994.It is on theWorld Health Organization's List of Essential Medicines.