Alfuzosin is an active substance belonging to the alpha-blocker class, used for the treatment of symptoms associated with benign prostatic hyperplasia (BPH). It relaxes the smooth muscle of the prostate and urethra, thereby increasing urinary flow, improving voiding, and alleviating storage symptoms. The effects have a rapid onset. Alfuzosin may lower blood pressure and consequently lead to adverse effects such as syncope, drowsiness, weakness, dizziness, malaise, and headache.
Alfuzosin (ATC G04CA01) acts as a selective antagonist at postsynaptic α1-adrenoreceptors, thereby relaxing the smooth muscle of the prostate and urethra. This increases urinary flow and improves both voiding and storage symptoms. Compared with 5-alpha reductase inhibitors, the effects have a rapid onset, occurring within hours to days. Alfuzosin has no effect on prostate size and is effective only against symptoms. Alfuzosin may lower blood pressure (see Adverse Effects).
⚠️ Warnings
•Caution should be exercised in patients with history of irregular heartbeat, prostate cancer, chest pain, low blood pressure, heart or kidney disease, any allergy, who are taking other medications and children.
Alfuzosin is prescribed only for men .Women must not take this medicine especially during pregnancy and lactation.
Avoid driving a car or operating machinery and get up slowly from bed while taking this medication as it may cause dizziness and lightheadedness.
Avoid situations in which injury could occur because of fainting.
Rarely, it may cause prolonged or painful erection; if so consult your doctor.
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