What is Famiflux used for?

- Prevention of recurrent duodenal ulcers - Duodenal ulcer - Benign gastric ulcer - Zollinger-Ellison syndrome - Symptomatic treatment of mild reflux oesophagitis

What pharmaceutical form is Famiflux available in?

Famiflux: Tabletki powlekane 20 mg (doustna)

Is Famiflux OTC or prescription only?

Famiflux is available over-the-counter (OTC) — no prescription required.

What are the side effects of Famiflux?

Tabulated list of adverse reactions Frequencies are defined as common (≥ 1/100 to < 1/10); uncommon (≥ 1/1,000 to < 1/100); rare (≥ 1/10,000 to < 1/1,000); very rare (< 1/10,000), not known (cannot be estimated from the available data). System Organ Class Common Uncommon Rare Very rare Blood and lymphatic system disorders Leukopenia, thrombocytopenia, neutropenia, agranulocytosis, pancytopenia Immune system disorders Hypersensitivity reactions (anaphylaxis, angioneurotic oedema, bronchospasm) Me

Who should NOT take Famiflux?

• Hypersensitivity to the active substance or to any of the excipients listed in section 6.1. • Patients with a history of hypersensitivity to other H 2 -receptor antagonists.

Does Famiflux interact with other medications?

No drug interactions of clinical importance have been identified. Famotidine does not interact with the cytochrome P450-linked drug metabolizing enzyme system. Compounds metabolized by this system which have been tested in man have included warfarin, theophylline, phenytoin, diazepam, propranolol, aminopyrine and antipyrine. Indocyanine green as an index of hepatic blood flow and/or hepatic drug extraction has been tested and no significant effects have been found. Studies in p

Can Famiflux be used during pregnancy?

Pregnancy Famotidine is not recommended for use in pregnancy, and should be prescribed only if clearly needed. Before a decision is made to use famotidine during pregnancy, the physician should weigh the potential benefits from the drug against the possible risks involved. Breast-feeding Famotidine is detectable in human milk. Nursing mothers should either stop this drug or stop nursing.

What precautions should be taken with Famiflux?

Any unused product or waste material should be disposed of in accordance with local requirements.

What ATC class does Famiflux belong to?

Famiflux: ATC A02BA03. ATC is the WHO Anatomical Therapeutic Chemical classification — it groups drugs by organ system and pharmacological mechanism.

Famiflux

This information is for educational purposes only. It is not intended as medical advice. Always consult a qualified healthcare professional.

Famiflux — Description, Dosage, Side Effects | PillsCard

Pharmacotherapeutic group: histamine H 2 -receptor antagonist, guanylthiazole derivative, ATC code: A02BA03 Mechanism of action Famotidine is a competitive histamine H 2 -receptor antagonist which leads to an inhibition of acid secretion mediated by H 2 -receptors.‍‍‍‍‍‍‍ Beside the acidity the pepsin content and the volume of basal gastric juice as well as that formed after stimulation is reduced. A pharmacological effect on the CNS, immunological, cardiovascular or respiratory parameters could not be observed. Pharmacodynamic effects, clinical efficacy and safety After oral administration the effect begins within one hour and reaches its maximum after 1-3 hours. Single oral doses of 20 and 40 mg reliably inhibited basal nocturnal acid secretion. Mean gastric acid secretion was inhibited over at least 10 hours by 86 to 94%. The same doses administered in the morning suppressed the acid secretion stimulated by food 3-5 hours after administration by, on average, 76 to 84% and 8-10 hours after ingestion by 25 to 30%. However, the duration of action of the 20 mg dose in some subjects lasted 6-8 hours. Repeated doses did not lead to an accumulation of active constituent. The nocturnal basal intragastric pH value was elevated by evening administration of 20 and 40 mg famotidine to an average of 5 and 6.4 respectively. If famotidine was taken after breakfast the pH value after 3 and after 8 hours was increased on the 20 mg as well as the 40 mg dose of famotidine to about 5. Fasting and postprandial serum gastrin concentrations were not influenced by famotidine or only very slightly. Emptying of the stomach and exocrine pancreatic function were not affected by famotidine. The same applies to hepatic and portal blood flow. Famotidine had no effect on endocrinological functions either. Hormone concentrations of prolactin, cortisone, thyroxine (T4) and testosterone remained unchanged on treatment with famotidine.

Famiflux

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