11 DESCRIPTION Almotriptan tablets, USP contain almotriptan malate, a selective 5-hydroxytryptamine 1B/1D (5-HT 1B/1D ) receptor agonist. Almotriptan malate is chemically designated as 1-[[[3-[2-(Dimethylamino)ethyl]-1H-indol-5-yl]methyl]sulfonyl]pyrrolidine (±)-hydroxybutanedioate (1:1) and its structural formula is: Its molecular formula is C 17 H 25 N 3 O 2 S•C 4 H 6 O 5 , representing a molecular weight of 469.56. Almotriptan malate, USP is a white to light yellow color crystalline powder that is soluble in water. Almotriptan tablets for oral administration contain 8.75 mg or 17.50 mg of almotriptan malate equivalent to 6.25 mg or 12.5 mg of almotriptan, respectively. Each compressed tablet contains the following inactive ingredients: hypromellose, mannitol, microcrystalline cellulose, polyethylene glycol, povidone, sodium starch glycolate (potato), sodium stearyl fumarate and titanium dioxide. Almotriptan Malate Structural Formula
⚠️ Warnings
• Caution should be exercised in patients with history of hypersensitivity to sulfonamides, liver or kidney impairment, seizures; children, pregnancy and breastfeeding.
• It may significantly increase blood pressure. Monitor blood pressure level regularly.
• It may cause drowsiness, do not drive a car or operate machinery while taking this medication.
Patient may develop with increased risk of Serotonin Syndrome with the following symptoms: increased heart rate, shivering, sweating, dilated pupils,etc . If it is so consult with your healthcare provider.