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ATC Code
B01AD12
Source
EMA · EMEA/V/C/000136
Thepharmacologyofestradiol, anestrogenmedication andnaturally occurringsteroid hormone, concerns itspharmacodynamics,pharmacokinetics, and variousroutes of administration.
Estradiol is anaturally occurringandbioidenticalestrogen, or anagonistof theestrogen receptor, thebiological targetofestrogenslikeendogenousestradiol.Due to its estrogenic activity, estradiol hasantigonadotropiceffects and can inhibitfertilityand suppresssex hormoneproductionin both women and men.Estradiol differs from non-bioidentical estrogens likeconjugated estrogensandethinylestradiolin various ways, with implications fortolerabilityandsafety.
Estradiol can be takenby mouth,held under the tongue, as agelorpatchthat isapplied to the skin,in through the vagina, byinjection into muscleorfat, or through the use of animplant that is placed into fat, among other routes.