What is Implanon NXT used for?

Contraception. Safety and efficacy have been established in women between 18 and 40 years of age.

What is the active ingredient in Implanon NXT?

Etonogestrelum (Etonogestrelum)

What pharmaceutical form is Implanon NXT available in?

Implanon NXT: Implant 68 mg (podskórna)

Is Implanon NXT OTC or prescription only?

Implanon NXT requires a doctor's prescription.

What are the side effects of Implanon NXT?

During the use of Nexplanon, women are likely to have changes in their menstrual bleeding pattern which are unpredictable beforehand. These may include the occurrence of an irregular bleeding pattern (absent, less frequent, more frequent or continuous), and changes in bleeding intensity (reduced or increased) or duration. Amenorrhoea was reported in about 1 of 5 women while another 1 of 5 women reported frequent and/or prolonged bleeding. Occasionally, heavy bleeding has been r

Who should NOT take Implanon NXT?

• Active venous thromboembolic disorder. • Known or suspected sex steroid sensitive malignancies. • Presence or history of liver tumours (benign or malignant). • Presence or history of severe hepatic disease as long as liver function values have not returned to normal. • Undiagnosed vaginal bleeding. • Hypersensitivity to the active substance or to any of the excipients listed in section 6.1.

Does Implanon NXT interact with other medications?

Note: The prescribing information of concomitant medications should be consulted to identify potential interactions. Effects of other medicinal products on Nexplanon Interactions can occur with drugs that induce microsomal enzymes which can result in increased clearance of sex hormones and which may lead to menstrual bleeding and / or contraceptive failure. Management Enzyme induction can already be observed after a few days of treatment. Maximum enzyme induction is generally o

Can Implanon NXT be used during pregnancy?

Pregnancy Nexplanon is not indicated during pregnancy. If pregnancy occurs during use of Nexplanon, the implant should be removed. Animal studies have shown that very high doses of progestagenic substances may cause masculinisation of female foetuses. Extensive epidemiological studies have revealed neither an increased risk of birth defects in children born to women who used OCs prior to pregnancy, nor of a teratogenic effect when OCs were inadvertently used during pregnancy. A

What precautions should be taken with Implanon NXT?

See section 4.2. The applicator is for single use only. Any unused medicinal product or waste material should be disposed of in accordance with local requirements.

Who manufactures Implanon NXT?

Organon Polska Sp. z o.o. (Holandia)

What ATC class does Implanon NXT belong to?

Implanon NXT: ATC G03AC08. ATC is the WHO Anatomical Therapeutic Chemical classification — it groups drugs by organ system and pharmacological mechanism.

Implanon NXT

This information is for educational purposes only. It is not intended as medical advice. Always consult a qualified healthcare professional.

Implanon NXT — Description, Dosage, Side Effects | PillsCard

Pharmacotherapeutic group: Hormonal Contraceptives for Systemic Use, progestagens, ATC code: G03AC08 Mechanism of action The Nexplanon implant is a non-biodegradable, radiopaque, etonogestrel-containing implant for subdermal use, preloaded in a sterile, disposable applicator.‍‍‍‍‍‍‍‍ Etonogestrel is the biologically active metabolite of desogestrel, a progestagen widely used in OCs. It is structurally derived from 19-nortestosterone and binds with high affinity to progesterone receptors in the target organs. The contraceptive effect of etonogestrel is primarily achieved by inhibition of ovulation. Ovulations were not observed in the first two years of use of the implant and only rarely in the third year. Besides inhibition of ovulation, etonogestrel also causes changes in the cervical mucus, which hinders the passage of spermatozoa. Clinical efficacy and safety Clinical trials were conducted in women between 18 and 40 years. Although no direct comparison was made, the contraceptive efficacy appeared to be at least comparable to that known for combined OCs. During the clinical studies no pregnancies were observed during 35,057 cycles of exposure; the Pearl Index observed is 0.00 (95 % confidence limits: 0.00-0.14). However, it must be realised that in practice no method can be considered 100 % effective. The high degree of protection against pregnancy is obtained, amongst other reasons, because the contraceptive action of Nexplanon is not dependent on adherence to a dosing regimen by the woman herself. The contraceptive action of etonogestrel is reversible, which is apparent from the rapid return of the normal menstrual cycle after removal of the implant. Although etonogestrel inhibits ovulation, ovarian activity is not completely suppressed. Mean oestradiol concentrations remain above the level seen in the early-follicular phase. In a two-year study, in which the bone mineral density in 44 users has been compared to that in a control group of 29 IUD-users no adverse effects on bone mass have been observed. No clinically relevant effects on lipid metabolism have been observed. The use of progestagen-containing contraceptives may have an effect on insulin resistance and glucose tolerance. Clinical trials further indicate that users of Nexplanon often have a less painful menstrual bleeding (dysmenorrhoea).

Implanon NXT

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