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Cautions and warnings: Consult a healthcare practitioner prior to use of you are pregnant; if you are taking antiplatelet medication or blood thinners; if you have gallstones or a bile duct obstruction; if you have stomach ulcers or excess stomach acid; or you are taking any other medications or natural health products, as black pepper/piperine may alter their effectiveness. Do not use if seal is broken. Keep out of reach of children.