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Tamper Evident: Product is sealed within a vial. Do not use if any part of the vial is torn, open or damaged. When first taking Culturelle, you may experience minor bloating, gas or intestinal gurgling which should subside with continued use. Consult your healthcare professional if symptoms persist after two weeks. For questions, concerns or to report an adverse event, please call (800) 722-3476. www.Culturelle.com Keep out of reach of children. Inform a healthcare professional before starting any dietary supplement, particularly if there is a known immune-compromised condition. Not a reduced calorie food.