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Cautions and warnings: Some patients experience nausea or gastrointestinal upset and drowsiness when taking 5-HTP. If this occurs, please discuss dosing with your healthcare practitioner. Please consult your healthcare practitioner before using this product if you are taking medications or supplements that have serotonergic activity; these include many antidepressants, St. John's wort, L-tryptophan, cold medications containing the ingredient dextromethorphan and some antimigraine medications. Consult your healthcare practitioner before using if you are pregnant or breast-feeding. Do not use if seal is broken. Keep out of reach of children.