USDailyMed:Testosterone
AU:DContraindicateddue toteratogeniceffects
G03BA03(WHO)
BR:Class C5(Anabolic steroids)CA:Schedule IVUK:Class CUS:Schedule IIIEU:Rx-onlyIn general: ℞ (Prescription only)
(8R,9S,10R,13S,14S,17S)-17-hydroxy-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one
58-22-0Y57-85-2(propionate)315-37-7(enanthate)58-20-8(cypionate)5949-44-0(undecanoate)
6013
2858
DB00624Y
5791Y
3XMK78S47O
D00075Y
CHEBI:17347Y
ChEMBL386630Y
Interactive image
O=C4\C=C2/[C@]([C@H]1CC[C@@]3([C@@H](O)CC[C@H]3[C@@H]1CC2)C)(C)CC4
InChI=1S/C19H28O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h11,14-17,21H,3-10H2,1-2H3/t14-,15-,16-,17-,18-,19-/m0/s1YKey:MUMGGOZAMZWBJJ-DYKIIFRCSA-NY
Testosteroneis amedicationand naturally occurringsteroid hormone.It is used to treatmale hypogonadism,gender dysphoria, and certain types ofbreast cancer.It may also be used to increaseathletic abilityin the form ofdoping.It is unclear if the use of testosterone forlow levels due to agingis beneficial or harmful.Testosterone can be administered through several different routes, includingtopicalgelsorpatches,nasal sprays, subdermal implants, ortablets dissolved inside the mouth.Testosterone therapy has been associated with improvements indepressive symptoms(especially inhypogonadalmen), increased exercise capacity and muscle strength in men withchronic heart failure, andmale contraceptioneffectiveness.
Commonside effectsof testosterone includeacne,swelling, andbreast enlargement in men.Serious side effects may includeliver toxicity,heart disease, and behavioral changes.Women and children who are exposed may developmasculinization.It is recommended that individuals withprostate cancershould not use the medication.It can cause harm to the baby if used duringpregnancyorbreastfeeding.Testosterone is in theandrogenfamily of medications.
Testosterone was first isolated in 1935, and approved for medical use in 1939.Rates of use have increased three times in the United States between 2001 and 2011.It is on theWorld Health Organization's List of Essential Medicines.It is available as ageneric medication.In 2023, it was the 119th most commonly prescribed medication in the United States, with more than 5million prescriptions.
