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Manufacturer
Chartwell RX, LLC.
ATC Code
J01FA09
Source
OPENFDA_NDC
USDailyMed:Clarithromycin
AU:B3
J01FA09(WHO)
AU:S4(Prescription only)CA:℞-onlyUS:℞-onlyEU:Rx-onlyIn general: ℞ (Prescription only)
(3R,4S,5S,6R,7R,9R,11S,12R,13S,14R)-6-{[(2S,3R,4S,6R) -4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy} -14-ethyl-12,13-dihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy -4-methoxy-4,6-dimethyloxan-2-yl]oxy}-7 -methoxy-3,5,7,9,11,13-hexamethyl -1-oxacyclotetradecane-2,10-dione
81103-11-9Y
84029
DB01211Y
10342604N
H1250JIK0A
D00276Y
ChEMBL1741N
DTXSID3022829
Interactive image
CC[C@@H]1[C@@]([C@@H]([C@H](C(=O)[C@@H](C[C@@]([C@@H]([C@H]([C@@H]([C@H](C(=O)O1)C)O[C@H]2C[C@@]([C@H]([C@@H](O2)C)O)(C)OC)C)O[C@H]3[C@@H]([C@H](C[C@H](O3)C)N(C)C)O)(C)OC)C)C)O)(C)O
InChI=1S/C38H69NO13/c1-15-26-38(10,45)31(42)21(4)28(40)19(2)17-37(9,47-14)33(52-35-29(41)25(39(11)12)16-20(3)48-35)22(5)30(23(6)34(44)50-26)51-27-18-36(8,46-13)32(43)24(7)49-27/h19-27,29-33,35,41-43,45H,15-18H2,1-14H3/t19-,20-,21+,22+,23-,24+,25+,26-,27+,29-,30+,31-,32+,33-,35+,36-,37-,38-/m1/s1NKey:AGOYDEPGAOXOCK-KCBOHYOISA-NN
Clarithromycin, sold under the brand nameBiaxinamong others, is anantibioticused to treat variousbacterialinfections.This includesstrep throat,pneumonia, skin infections,H. pyloriinfection, andLyme disease.Clarithromycin can be taken by mouth as a tablet or liquid or can be infused intravenously.
Common side effects include nausea, vomiting, headaches, and diarrhea.Severeallergic reactionsare rare.Liver problems have been reported.It may cause harm if taken duringpregnancy.It is in themacrolideclass and works by slowing down bacterialprotein synthesis.Clarithromycin resistance is already a major challenge to healthcare systems and such resistance is spreading, leading to recommendations to test the susceptibility of pathogenic organisms to the antibiotic before commencing clarithromycin therapy.
Clarithromycin was developed in 1980 and approved for medical use in 1990.It is on theWorld Health Organization's List of Essential Medicines.Clarithromycin is available as a generic medication.It is made fromerythromycinand is chemically known as 6-O-methylerythromycin.