This information is for educational purposes only. It is not intended as medical advice. Always consult a qualified healthcare professional.
Description, Dosage, Side Effects, Contraindications. Data from EMA, URPL, openFDA and other regulatory sources.
| Clarithromycin | Azithromycin | |
|---|---|---|
| Active Substances | CLARITHROMYCIN | AZITHROMYCIN |
| ATC Code | J01FA09 | J01FA10 |
| Form | TABLET | SOLUTION/DROPS |
| Dosage | 250MG | 1% |
| Route | ORAL | OPHTHALMIC |
| Manufacturer | AUROBINDO PHARMA LTD | THEA PHARMA INC |
| Indications | This medication is a macrolide antibiotic, prescribed infections of the middle ear, tonsillitis, throat infections, laryngitis, bronchitis, pneumonia, and skin infections. It stops the growth of sensitive bacteria. | This medication is a macrolide antibiotic used for various bacterial infections such as infections of the middle ear, throat, bronchus, sinuses, skin and soft tissue. It is also useful in treating pneumonia, typhoid, gonorrhoea, granuloma inguinale and chancroid. It prevents bacterial growth. |
| Side Effects | Most Common - Nausea, diarrhea, abnormal taste, stomach upset, abdominal pain and headache. Central Nervous System - Mood changes, tremor, dizziness, confusion, seizures, sleeplessness, hallucinations, nightmares, tinnitus (abnormal sounds within the ears). Liver - Liver inflammation with or without jaundice, increase in liver enzymes. Metabolic - Low sugar. Heart - QT prolongation, abnormal heart rhythm. Genitourinary - Kidney damage. Miscellaneous - Fever, flu-like symptoms, blisters, itching, allergic reactions, hearing loss, secondary intestinal infection. |
Clarithromycin (INN: CLARITHROMYCIN, ATC J01FA09) and Azithromycin (INN: AZITHROMYCIN, ATC J01FA10) differ in active substance, indications, and safety profile. The table above summarizes the clinical differences from regulatory documents.
Combination safety depends on mechanisms and your health profile. Use our interactions checker and always consult your doctor or pharmacist before combining medications.
Both drugs are approved when used per label. Safety is patient-specific — the better choice depends on your condition, other medications, allergies, and comorbidities. Consult a healthcare professional for personalized advice.
This information is for educational purposes only. It is not intended as medical advice. Always consult a qualified healthcare professional.
| Heart - Chest pain, abnormal heart rate, low blood pressure, abnormal heart rhythm with QT prolongation and torsades de pointes. Gastrointestinal - Indigestion, loss of appetite, flatulence, gastritis, loose stools, vomiting, colitis and constipation. Genitourinary - Kidney failure and vaginal inflammation. Blood - Decrease in platelets. Liver - Abnormal liver function, jaundice and liver failure. Central Nervous System - Weakness, tingling, fatigue, uneasiness, dizziness/vertigo, headache, drowsiness, hyperactivity, nervousness, agitation and syncope. Skin - Itching, severe allergic reactions, irritation, fungal infection, sweating, hives and blistering. ENT - Hearing loss and/or tinnitus, abnormalities in taste and smell sensation. Hypersensitivity - Allergic reaction. Respiratory - Increased cough, inflammation of pharynx, pleural effusion and rhinitis. |
| Warnings | •This product may contain tartrazine dye. This may cause an allergic reaction in some patients. • Long-term or repeated use of this medication should be avoided. • Caution should be exercised in patients with history of liver or kidney disease, resistance to other drugs of the same group, pregnancy, lactation, children. | •Caution should be exercised in patients with history of cystic fibrosis, human immunodeficiency virus (HIV), irregular heartbeat, or kidney or liver disease, during pregnancy and breastfeeding. |
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