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金馬化學製藥股份有限公司蘆竹廠 (TW)
ATC Code
A03FA01
Source
TFDA
USDailyMed:Metoclopramide
AU:A
A03FA01(WHO)
AU:S4(Prescription only)CA:℞-onlyUK:POM(Prescription only)US:℞-only
4-Amino-5-chloro-N-(2-(diethylamino)ethyl)-2-methoxybenzamide
364-62-5Y
4168
241
DB01233Y
4024Y
L4YEB44I46
D00726Yas HCl:D05008Y
CHEBI:107736Y
ChEMBL86Y
DTXSID6045169
Interactive image
Clc1cc(c(OC)cc1N)C(=O)NCCN(CC)CC
InChI=1S/C14H22ClN3O2/c1-4-18(5-2)7-6-17-14(19)10-8-11(15)12(16)9-13(10)20-3/h8-9H,4-7,16H2,1-3H3,(H,17,19)YKey:TTWJBBZEZQICBI-UHFFFAOYSA-NY
Metoclopramideis amedicationused to treat nausea, vomiting,gastroparesis, andgastroesophageal reflux disease.It is also used to treatmigraineheadaches.
Common side effects include feeling tired,diarrhea, andakathisia. More serious side effects includeneuroleptic malignant syndrome,tardive dyskinesia, anddepression.It is thus rarely recommended that people take the medication for longer than twelve weeks.No evidence of harm has been found after being taken by many pregnant women.It belongs to the group of medications known asdopamine receptor antagonistsand works as aprokinetic.
In 2012, metoclopramide was one of the top 100 most prescribed medications in the United States.It is available as ageneric medication.It is on theWorld Health Organization's List of Essential Medicines.In 2023, it was the 256th most commonly prescribed medication in the United States, with more than 1million prescriptions.
⚠️ Warnings
•Caution needed for children, elderly, patients with history of liver or kidney disease, porphyria (group of inherited or acquired disorders of certain enzymes), epilepsy, Parkinson's disease, diabetes, history of depression.
It may cause dizziness. Do not drive a car or operate machinery until you know how this medication affects you.
Do not drink alcohol or use medicines that may cause drowsiness.
Do not take more than the recommended dose or use this medication for longer than 12 weeks without checking with your doctor.
Avoid prolong usage of this medication, otherwise it may lead to involuntary movements.