Cefalotin

AU:A J01DB03(WHO) AU:S4(Prescription only)UK:POM(Prescription only) (6R,7R)-3-[(acetoxy)methyl]-8-oxo-7-[(2-thienylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 153-61-7Y 6024 DB00456Y 5802Y R72LW146E6 D07635Y CHEBI:124991Y ChEMBL617Y DTXSID4022783 Interactive image O=C2N1/C(=C(\CS[C@@H]1[C@@H]2NC(=O)Cc3sccc3)COC(=O)C)C(=O)O InChI=1S/C16H16N2O6S2/c1-8(19)24-6-9-7-26-15-12(14(21)18(15)13(9‍‍‍‍‍‍​​​‍​​​​​​)16(22)23)17-11(20)5-10-3-2-4-25-10/h2-4,12,15H,5-7H2,1H3,(H,17,20)(H,22,23)/t12-,15-/m1/s1YKey:XIURVHNZVLADCM-IUODEOHRSA-NY Cefalotin(INN)/ˌsɛfəˈloʊtɪn/orcephalothin(USAN)/ˌsɛfəˈloʊθɪn/is a first-generationcephalosporinantibioticwith broad spectrum antibiotic activity.It was the first cephalosporin marketed (1964) and continues to be widely used.Cefalotin is used for bacterial infections of the respiratory tract, urinary tract, skin, soft tissues, bones and joints, sepsis, peritonitis, osteomyelitis, mastitis, infected wounds, and post-operational infections. It is anintravenouslyadministered agent with a similar antimicrobial spectrum tocefazolinand the oral agentscefalexinandcefadroxil.Cefalotin sodiumis marketed asKeflin(Lilly) and under other trade names. The compound is a derivative ofthiophene-2-acetic acid.