Diclofenac vs Ibuprofen

Q: What is the difference between Diclofenac and Ibuprofen?

Diclofenac (INN: DICLOFENAC SODIUM, ATC D11AX18) and Ibuprofen (INN: IBUPROFEN, ATC C01EB16) differ in active substance, indications, and safety profile. See the side-by-side table below for dosage, contraindications, and side effects.

Q: Can I take Diclofenac and Ibuprofen together?

Combination safety depends on both drugs' mechanisms and your health profile. Check interactions in our database and always consult your doctor or pharmacist before combining.

Q: Which is safer, Diclofenac or Ibuprofen?

Safety is patient-specific — both drugs are approved by regulatory authorities when used per label. The better choice depends on your condition, other medications, allergies, and comorbidities. Consult a healthcare professional for personalized advice.

Description, Dosage, Side Effects, Contraindications. Data from EMA, URPL, openFDA and other regulatory sources.

e.g. HealthdirectFree Australian health advice you can count on.

	Diclofenac	Ibuprofen
Active Substances	DICLOFENAC SODIUM	IBUPROFEN
ATC Code	D11AX18	C01EB16
Form	SOLUTION/ DROPS	TABLET, COATED
Dosage	1 mg/mL	200 mg/1
Route	OPHTHALMIC	ORAL
Manufacturer	Altaire Pharmaceuticals Inc.	Haleon US Holdings LLC
Indications	( ARTG ) The suppression of voluntary muscle spasm in: multiple sclerosis, spinal lesions of traumatic, infectious, dege‍‍‍‍‍‍‍nerative, neoplastic and unknown origin, causing: Skeletal hypertonus, Spastic and dyssynergic bladder dysfunction. Baclofen is not recommended in Parkinson's disease or spasticity arising from strokes, cerebral palsy or rheumatoid disorders.	—
Side Effects	You can help ensure medicines are safe by reporting the sid‍‍‍‍‍‍‍e effects you experience. You can report side effects to your doctor, or directly at www.tga.gov.au/reporting-problems

FAQ

What is the difference between Diclofenac and Ibuprofen?

Diclofenac (INN: DICLOFENAC SODIUM, ATC D11AX18) and Ibuprofen (INN: IBUPROFEN, ATC C01EB16) differ in active substance, indications, and safety profile. The table above summarizes the clinical differences from regulatory documents.

Can I take Diclofenac and Ibuprofen together?

Combination safety depends on mechanisms and your health profile. Use our interactions checker and always consult your doctor or pharmacist before combining medications.

Which is safer, Diclofenac or Ibuprofen?

Both drugs are approved when used per label. Safety is patient-specific — the better choice depends on your condition, other medications, allergies, and comorbidities. Consult a healthcare professional for personalized advice.

This information is for educational purposes only. It is not intended as medical advice. Always consult a qualified healthcare professional.